Dr. Jaya Bandyopadhyay

Department of Biotechnology

Associate Professor

Department of Biotechnology
Maulana Abul Kalam Azad University of Technology, West Bengal
(formerly known as West Bengal University of Technology)
BF 142, Salt Lake City, Sector I, Kolkata 700 064  (City Office)
NH 12, Haringhata, Post Office - Simha

jaya.bandyopadhyay@gmail.com

Research Area: Molecular Cell Biology
Molecular Development
Neurotoxicology
Nanobiotechnology

About Dr. Jaya Bandyopadhyay

Dr. Jaya Bandyopadhyay is currently working in the position of Associate Professor in the Department of Biotechnology, at Maulana Abul Kalam Azad University of Technology, West Bengal (formerly WBUT). She has been teaching in this department for more than 17 years and from the very inception of the Biotechnology Department since 2002. Dr. Bandyopadhyay was awarded Ph.D in 1995 from the Department of Zoology (School of Life Sciences), Visva Bharati University, Santiniketan. She has post-doctoral trainings from South Korea (Chonnam National University and Gwangju Institute of Science & Technology, GIST) for more than 5 years (1995-2001) and further worked as a Visiting Scholar in GIST and Hanyang University, Seoul, South Korea for 1 year (2007-2008) under the Brain Pool Scheme funded by the Korean Federation of Science & Technology Societies (KOFST). She also worked in the Indian Institute of Chemical Biology (Kolkata) as a CSIR Senior Research Associate (CSIR Scientist’s Pool Scheme) from 2001-2002 before joining as a Lecturer in WBUT.
Presently, Dr. Bandyopadhyay has 7 Ph.D students working under her supervision in the fields of molecular aging and stress-induced neurodegeneration using the nematode Caenorhabditis elegans (C. elegans) and mammalian cell systems, respectively. Dr. Bandyopadhyay is also studying the interaction properties of DNA with various nanotubes and their impacts on C. elegans, and investigating the antibacterial activity of Graphene based nanomaterials and its impact on animal models. She is further exploring the molecular mechanism of metal / chemical induced neurotoxicity with a view to search natural products as promising drug candidates using mammalian cell systems.

Specialization
Molecular Cell Biology, Genetic Engineering, Cell Signalling

Research Collaborators (National):
1. Prof. (Dr.) Debashis De (Professor, CSE Department, MAKAUT,WB),
2. Dr. Soumalee Basu, Assistant Professor, Dept. of Microbiology, University of Calcutta, Kolkata,
3. Dr. Angsuman Sarkar, Associate Professor, Department of Electronics & Communication Engg, Kalyani Govt. Engg. College, Kalyani.

4. Prof. Pintu Sen, Scientific Officer H, Professor, Homi Bhabha National Institute, Variable Energy Cyclotron Centre, 1/AF, Bidhan Nagar, Kolkata - 700 064, India.
5. Dr Dambarudhar Mohanta, Associate Professor, Department of Physics, Tezpur University, Assam.
6. Prof. Tarun Kanti Bhattacharya, Dept of Electronics & Electrical Communication Engg., Advanced Technology Development Centre, Prof-in-charge, Advanced VLSI Laboratory National MEMS Design Centre, IIT Kharagpur, West Bengal, India
7. Dr. Samir Chandra Das, System Manager, Centre for Research in Nanoscience and Nanotechnology (CRNN), University of Calcutta, JD-2, Salt Lake City, Kolkata 700098, West Bengal, India
8. Dr. Partha Pratim Parui, Department of Chemistry, Jadavpur University, West Bengal, India

Research Collaborators (International):
1. Department of Bioengineering, Hanyang University with Department of Biotechnology, MAKAUT, W.B.
2. Department of Life Science, Hanyang University with Department of Biotechnology, MAKAUT, W.B.

Publications: View at Google Scholar
Ph.D. Students

1. Jyotirmoy Rakshit
2. Kunal Biswas
3. Swati Sinha
4. Tanaya Paul
5. Sourav Pakrashi
6. Joyeeta Chakraborty
7. Swagata Roychowdhury

Post-Doctoral Fellow:
Dr. Susmita Roy (DST N-PDF): Broad area of research: Immunomodulatory roles of candidate genes in Down syndrome patients giving special emphasis to T cell activation.
Membership in Scientific Bodies
1. Member of the Editorial Board of “Animal Cells and Systems” Journal; Publisher Taylor and Francis.
2. Life Member of the Society for Biological Chemists (India).
3. Member of the Genetics Society of America

Invited Talk (Foreign)
i) Participation as plenary speaker – First International Conference and Exhibition of Organisation for Women in Science for the Developing World (OWSD). Conference Date: 3-6 June, 2013; Venue: Elf Lecture Theater, Main Campus, University of Uyo, Uyo, Akwa Ibom State, Nigeria. Title of the paper: Caenorhabditis elegans as a model organism to study sterol transport and metabolism in development: Implications for Peptidyl prolyl cis-trans isomerase 1 (Pin-1) as a negative modulator.
ii) Nramp-like Metal Transporters in C. elegans: a model for studying Mn-mediated innate immunity. J Bandyopadhyay*, J Ahnn, and JH Cho. 2010. 1st International Conference on Model Hosts, Heraklion, Crete, Greece, Sep 05-Sep 10, 2010.
iii) Role of Calcium Binding Proteins in Multiple Aspects of Behavior in Caenorhabditis elegans. Jaya Bandyopadhyay* and Joohong Ahnn. Invited talk at “The 7th International Symposium on Developmental Biotechnology, October 26-27, 2007, Jeju University, Jeju, South Korea.”
iv) Cloning and Characterization of cDNA Encoding Rana P34CDC2 kinase, A component of the Maturation Promoting Factor. Jaya Bandyopadhyay*, Arun Bandyopadhyay, Hae-Mook Kang, Heung-Sik Choi and Hyuk Bang Kwon. 1998. Invited talk at The Third International Symposium for Asia and Oceania Society for Comparative Endocrinology Kwangju, Republic of Korea, September 22-25 (1998).
Invited Talk / Key note Address / Chairing Sessions (selected) (National):
i) Caenorhabditis elegans, an emerging animal model for biosensing studies. Invited talk at the CCSN2018: 7th International Conference on Computing, Communication and Sensor Network, held at Biswa Bangla Convention Centre on 27th – 28th October, 2018; Session: “Biotechnology and Image Sensing”.
ii) Chaired the session at The Second Indian C. elegans meeting, 2018 at NII, New Delhi during 23rd – 26th February, 2018 on Neuronal Trafficking and Protein Aggregation.
iii) C. elegans and Biogerontology: A Genetic Dissection to the Mechanism of Aging. Invited Resource person for Refresher Course in Life Sciences (thrust area: Challenges and options in Life Science Research in the developing world today) for college and university teachers during Dec. 23, 2016 - Jan.13, 2017.
iv) Analysing C. elegans behaviour as a parameter for treated water quality Testing: Invited talk at the Advanced Workshop on Microbial Technology for Clean Environment. Jointly Organized by COEETM, MAKAUT, WB and Tripura University, 18th to 21st September, 2017.
v) Chaired the session at The First Indian C. elegans meeting, 2016 at the 40th Mahabaleshwar Seminar during 30th January – 02nd February, 2016 on Molecules to Circuitry.
vi) Scope of Biotechnology in Food Processing and Food Safety: Recent Advances and the West Bengal Scenario. Invited talk at the Seminar on PROMOTION OF FOOD PROCESSING INDUSTRIES IN WEST BENGAL; Focus on Planning, New Technologies, Marketing Strategies; Sponsored by ICC & Department of Food Processing Industries & Horticulture, Government of West Bengal; 17th October 2012, Royal Bengal Room, City Center 1, Salt Lake, Kolkata
vii) Oxidative stress alters gene expression in human neuroblastoma cells. 2010. Invited talk at the 17th State Science & Technology Congress, Kolkata, March 4-5, Abstract BT19, Page 386.
viii) Invited speaker in a Workshop on Bioinformatics at Haldia Institute of Technology, Haldia (20-21 March, 2007) at the Department of Computer Science & Informatics, HIT, WB.




Papers presented at Conferences (selected)

i) Tanaya Paul*, Kunal Biswas, Sudhanshu Mishra, Swati Sinha and Jaya Bandyopadhyay. 2018. Thermo-chemical micro-sensing system of a biological model organism C. elegans towards a chemical stimulus. Paper presented in 7th International Conference on ‘Computing, Communication and Sensor Networks’, CCSN2018. Paper ID #07 (https://ccsnmicro.wixsite.com/ccsn2018). (*presenter)

ii) Single Layer Graphene Oxide (SLGO) nanosheet exhibited reduced altered locomotion, survivability and differential behavioral response compared to multilayered Graphene Oxide (GO) nanosheets in eukaryotic model C. elegans. Kunal Biswas*, Tanaya Paul, Sudhanshu Mishra, Arghajit Biswas, Debashis De, and Jaya Bandyopadhyay. Poster presentation at The Second Indian C. elegans meeting, 2018 at NII, New Delhi during 23rd – 26th February, 2018. (*presenter)

iii) Effects of 2-(ethylhexyl) phthalate in C. elegans on reducing health span, pharyngeal pumping and induction of ROS generation. Tanaya Paul*, Nayan Pandey and Jaya Bandyopadhyay. Poster presentation at The Second Indian C. elegans meeting, 2018 at NII, New Delhi during 23rd – 26th February, 2018. (*presenter)
Chapters in Books
i) Kunal Biswas, Debashis De and Jaya Bandyopadhyay. 2019. Graphene: A revolutionary 2D nanomaterial heralding a new horizon for diagnostics and therapeutic applications, In Nanotechnology in Biology and Medicine: Research Advancements & Future Perspectives. Pradipta Ranjan Rauta, Yugal Kishore Mohanta, Debasis Nayak (Eds), 1st Edition. Chapter 17: pp 205-214. (CRC Press, Taylor & Francis, ISBN 9780367200503) , DOI: 10.1201/9780429259333-17.
ii) Kunal Biswas, Siddharth Shaw, Shudhanshu Mishra, Debashis De and Jaya Bandyopadhyay. 2019. Theranostic advances of graphene based nanomaterial in diabetes. In Nanotechnology in Biology and Medicine: Research Advancements & Future Perspectives. Pradipta Ranjan Rauta, Yugal Kishore Mohanta, Debasis Nayak (Eds), 1st Edition, Chapter 15: pp.185-192 (CRC Press, Taylor & Francis, ISBN 9780367200503), 10.1201/9780429259333-15, DOI :10.1201/9780429259333-15.
iii) S. Sinha, J. Bandyopadhyay, and D. De. 2016. “DNA Computing Using Carbon Nanotube-DNA Hybrid Nanostructure,” In IGI Handbook of Research on Natural Computing for Optimization Problems, pp. 744-774.
iv) Jeong Hoon Cho and Jaya Bandyopadhyay. 2012. Animal Models for Salmonella Pathogenesis: Studies on the virulence properties using Caenorhabditis elegans as a model host. In Salmonella, A Diversified Superbug, Yashwant Kumar (Editor), Intech Publisher, Part 5, Chapter 22, pp 433-448. ISBN 979-953-307-691-0.
v) S Sen, S Mondal, J. Adhikari, D Sarkar, S Bose, B Mukhopadhyay and Shelley Bhattacharya. 1995. Inhibition of fish brain acetylcholinesterase by cadmium and mercury: Interaction with selenium. In Enzymes of Cholinesterase Family, Daniel Quinn et al (Eds), Plenum Press, New York, pp 369-374.

Extramural Research Grants



S. No.

Title.

Agency.

Period.

Grant / Amount (Rs. in lakhs).

1

Investigation of the activity of graphene and its derivatives towards the biological systems with special relevance to C. elegans.
(As PI)

Department of Higher Education, Science and Technology and Biotechnology, Government of West Bengal

2019-2022

Rs. 22.66

2

A Functional Study On Peptidyl Prolyl Cis/Trans Isomerase Pin1 Homologue In Caenorhabditis elegans.
(As PI)

CSIR

2011-2014

Rs. 19.5 lakhs


3

Molecular Mechanism of Thyroid hormone-induced Oxidative stress and Hypoxia in neuroblastomas: Identification of Differentially Expressed Genes by cDNA Array Analysis
(As PI)

UGC-Major


2012-2015

Rs. 10.938 lakhs


4

Isolation, biological properties and explorations of lectin–quantum dot nano conjugates as novel fluorescent marker for identification of cancer cells. (As Co-PI)

CSIR

2010-2014

Rs. 23.416 lakhs


5

Anti-amyloidogenic effects of some antioxidant phytochemicals present in common traditional plant: Implications for the prevention
and therapeutics of Alzheimer's Disease (AD). (As Co-PI)

Department of Science & Technology, Govt. of West Bengal


2011- 2014

Rs. 12.38 lakhs

6

Identification of novel BACE-1 inhibitors by simulating BACE1-flavonoid interaction to identify new pharmacophore model followed by virtual screening in 3-D ligand database – a de novo drug design approach.
(As Co-PI)

Department of Science & Technology, Govt. of India


2012-2015

Rs. 23.81 lakhs

7

In vitro studies of some Homeopathic drugs medicines on the proliferation and differentiation of neural stem cells.
(As Co-PI)

Central Council for Research in Homoeopathy (CCRH)

2012-2015

Rs.26.06 lakhs